
Professor
M_Biochemistry and Biophysics
+1 415 514-9708
Publications
Localization events-based sample drift correction for localization microscopy with redundant cross-correlation algorithm.
Optics express
Selective targeting of TGF-ß activation to treat fibroinflammatory airway disease.
Science translational medicine
Single particle electron cryo-microscopy of a mammalian ion channel.
Current opinion in structural biology
Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proceedings of the National Academy of Sciences of the United States of America
CTER-rapid estimation of CTF parameters with error assessment.
Ultramicroscopy
Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway.
Developmental cell
Influence of electron dose rate on electron counting images recorded with the K2 camera.
Journal of structural biology
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis.
Cell
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.
Nature methods
Recording high-resolution images of two-dimensional crystals of membrane proteins.
Methods in molecular biology (Clifton, N.J.)
A method for integrative structure determination of protein-protein complexes.
Bioinformatics (Oxford, England)
Self-assembly of filamentous amelogenin requires calcium and phosphate: from dimers via nanoribbons to fibrils.
Biomacromolecules
Fabs enable single particle cryoEM studies of small proteins.
Structure (London, England : 1993)
Visualizing proteins and macromolecular complexes by negative stain EM: from grid preparation to image acquisition.
Journal of visualized experiments : JoVE
Self-assembly of amelogenin proteins at the water-oil interface.
European journal of oral sciences
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.
The Journal of biological chemistry
A distributed multi-GPU system for high speed electron microscopic tomographic reconstruction.
Ultramicroscopy
Self-aligning amelogenin nanoribbons in oil-water system.
Journal of structural biology
Structure characterization of the 26S proteasome.
Biochimica et biophysica acta
HIV Rev response element (RRE) directs assembly of the Rev homooligomer into discrete asymmetric complexes.
Proceedings of the National Academy of Sciences of the United States of America
GPU-enabled FREALIGN: accelerating single particle 3D reconstruction and refinement in Fourier space on graphics processors.
Journal of structural biology
Collecting electron crystallographic data of two-dimensional protein crystals.
Methods in enzymology
HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells.
Traffic (Copenhagen, Denmark)
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.
The EMBO journal
Evaluation of imaging plates as recording medium for images of negatively stained single particles and electron diffraction patterns of two-dimensional crystals.
Journal of electron microscopy
Toward an atomic model of the 26S proteasome.
Current opinion in structural biology
A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis.
Biochimica et biophysica acta
The advent of near-atomic resolution in single-particle electron microscopy.
Annual review of biochemistry
A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies.
Proceedings of the National Academy of Sciences of the United States of America
In vitro self-assembly of tailorable nanotubes from a simple protein building block.
Proceedings of the National Academy of Sciences of the United States of America
Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.
Molecular cell
Polymorphic assemblies and crystalline arrays of lens tetraspanin MP20.
Journal of molecular biology
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.
Molecular cell
Reconstructing the endocytotic machinery.
Methods in cell biology
Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly.
Journal of molecular biology
Electron tomography of swollen rigor fibers of insect flight muscle reveals a short and variably angled S2 domain.
Journal of molecular biology
Structure determination of clathrin coats to subnanometer resolution by single particle cryo-electron microscopy.
Journal of structural biology
Three-dimensional structure of an AMPA receptor without associated stargazin/TARP proteins.
Biological chemistry
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.
Molecular cell
Single particle reconstruction of the human apo-transferrin-transferrin receptor complex.
Journal of structural biology
Single particle reconstructions of the transferrin-transferrin receptor complex obtained with different specimen preparation techniques.
Journal of molecular biology
Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating.
Nature
Aquaporin-0 membrane junctions form upon proteolytic cleavage.
Journal of molecular biology
A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase.
Journal of virology
Negative Staining and Image Classification - Powerful Tools in Modern Electron Microscopy.
Biological procedures online
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII.
Proceedings of the National Academy of Sciences of the United States of America
The three-dimensional map of microsomal glutathione transferase 1 at 6 A resolution.
The EMBO journal
The projection structure of the membrane protein microsomal glutathione transferase at 3 A resolution as determined from two-dimensional hexagonal crystals.
Journal of molecular biology
Influence of various nucleotides on the in situ crystallization of Ca2+-ATPase.
Biochimica et biophysica acta
The use of electron tomography for structural analysis of disordered protein arrays.
Journal of structural biology