People

Our research is focused on elucidating the mechanism of Hsp90 chaperone function and its role in human disease, microtubule nucleation & centrosome structure, and the structure and cell biology of phage-encoded tubulins. Accompanying this is an effort to develop new technologies for high-resolution cryoEM and fluorescence light microscopy.

Yifan Cheng Lab

Our lab focuses on understanding molecular chaperone-driven protein quality control mechanisms that facilitate protein folding and cellular stress responses.  A protein must fold into a native state or a range of three-dimensional states in order to carry out biological functions, and must retain a certain degree of flexibility to accommodate various chemistries and binding events.